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Models

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Mice

Ctsk-2A-CreERT2

Strain Name：C57BL/6Smoc-Ctskem1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200067
Publications：1piece

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ctsk gene stop codon site.

Mice

hPD-L1/hVISTA

Strain Name：C57BL/6Smoc-Visrtm1(hVSIR)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000094

hPD-L1(NM-HU-00062) was crossed with hVISTA(NM-HU-00118) to generate hPD-L1/hVISTA.

Mice

hFAS

Strain Name：C57BL/6Smoc-Fastm1(hTNFRSF6)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210007
Validation Data：Presence

The endogenous mice Fas gene was replaced by human FAS gene.

Mice

hICOS/hICOSL

Strain Name：C57BL/6Smoc-Icosltm1(hICOSLG) Icostm1(hICOS)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18018
Validation Data：Presence

This ICOS and ICOSL double knockin strain is established by crossing ICOS-HU and ICOSL-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hCD3E/hPD-L1

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210449
Validation Data：Presence

hCD3E(NM-HU-00114) was crossed with hPD-L1(NM-HU-00062) to generate hCD3E/hPD-L1 mice

Mice

Lyz2-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190041
Validation Data：Presence

A IRES-DTREGFP expression cassette was knocked into the Lyz2 gene stop codon site.

Mice

R26-CAG-LSL-hEGFR*L858R/T790M-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190068

These mice harbor a CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

hHER3(2)

Strain Name：C57BL/6Smoc-Erbb3tm2(hERBB3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225068
Validation Data：Presence

The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.

Mice

CAG-Dre-Tg

Strain Name：C57BL/6Smoc-Tg(CAG-Dre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00026

These transgenic mice carry Dre recombinase driven by CAG promoter.

Mice

hPD-L2(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1lg2tm1(hPDCD1LG2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190061

The endogenous mouse Pdcd1lg2 gene was replaced by human PDCD1LG2 gene.

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