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Models

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Mice

hCRLF2

Strain Name：C57BL/6JSmo-Crlf2tm1(hCRLF2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210028
Validation Data：Presence

The endogenous mice Crlf2 gene was completely or partially replaced by human CRLF2 gene via ESC targeting.

Mice

hSOST

Strain Name：C57BL/6JSmo-Sosttm1(hSOST)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200251
Validation Data：Presence

The endogenous mice Sost gene was replaced by human SOST gene. While hSOST(2)(Stock No.NM-HU-215021) mice function similarly to hSOST mice, for more detailed information please contact our technical advisor.

Mice

hIL17F

Strain Name：C57BL/6JSmo-Il17ftm2(hIL17F)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190007
Validation Data：Presence

The endogenous mouse Il17 gene was replaced by human IL17F gene.

Mice

Cd68-IRES-Cre

Strain Name：C57BL/6JSmo-Cd68em1(IRES-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200161

A IRES-Cre expression cassette was knocked into the Cd68 gene stop codon site.

Mice

hHER3(2)

Strain Name：C57BL/6JSmo-Erbb3tm2(hERBB3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225068
Validation Data：Presence

The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.

Mice

hPD-1/hTIGIT

Strain Name：C57BL/6JSmo-Pdcd1tm1(hPDCD1) Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00104

hPD-1(NM-HU-00015) was crossed with hTIGIT(NM-HU-00053) to generate hPD-1/hTIGIT.

Mice

hSERPINA1

Strain Name：C57BL/6JSmo-Serpina1etm1(hSERPINA1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225055
Validation Data：Presence

The endogenous mouse Serpina1e gene was replaced by human SERPINA1 gene.

Mice

R26-CreERT2

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200041
Validation Data：Presence

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment.

Mice

C4b-KO

Strain Name：C57BL/6JSmo-C4bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190761

Exon 3 of C4b gene was deleted to generate C4b knockout mice.

Mice

hCD248

Strain Name：C57BL/6JSmo-Cd248tm1(hCD248)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225028

The endogenous mouse Cd248 gene was replaced by human CD248 gene.

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