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Models

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Mice

hCD40L(BALB/c)

Strain Name：BALB/cAnSmoc-Cd40lgtm1(hCD40L)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000052

The endogenous mouse Cd40lg gene was replaced by human CD40L gene.

Mice

R26-TetO-Dre-IRES-mtagBFP2

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-pA-Ins-Ins-TetO-Dre-IRES-BFP-pA-Ins-Ins)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190020

The SA-polyA-Ins-Ins-TetO-Dre-IRES-BFP-polyA-Ins-Ins cassette is inserted in mouse Rosa26 loci.

Mice

hHLA-A11.1

Strain Name：C57BL/6Smoc-H2-K1tm1(hHLA-A*1101)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-204987
Validation Data：Presence

The endogenous mice H2-K1 gene was replaced by human HLA-A11.1 gene.

Mice

hIL4RA

Strain Name：C57BL/6Smoc-Il4ratm1(hIL4R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190008
Validation Data：Presence

The endogenous mouse Il4ra gene was replaced by human IL4R gene.

Mice

R26-CAG-LSL-dCas9-VPR-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)
Strain State：Repository Live | Cat. NO.：NM-KI-18004

These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

hCYP2D6

Strain Name：C57BL/6Smoc-Cyp2dtm(hCYP2D6)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215024

The endogenous mouse Cyp2d22 gene was replaced by human CYP2D6 gene.

Mice

hTIGIT(3)

Strain Name：C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200244
Validation Data：Presence

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT（3） mice ,for more detailed information please contact our technical advisor.

Mice

Cd200-KO

Strain Name：C57BL/6Smoc-Cd200em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190029

This Cd200 knockout mouse model was generated by knocking out the exon 2 region of the Cd200 .

Mice

hIL11RA

Strain Name：C57BL/6Smoc-Il11ra1tm1(hIL11RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204982

The endogenous mice Il11ra1 gene was replaced by human IL11RA gene.

Mice

hTNFRSF10B

Strain Name：C57BL/6Smoc-Tnfrsf10btm1(hTNFRSF10B)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210005

The endogenous mice Tnfrsf10B gene was replaced by human TNFRSF10B gene

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