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Mice

Ahi1-Flox

Strain Name：B6;129S-Ahi1tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00053

These mice possess loxP sites on either side of exon 3 the Ahi1 (Abelson helper integration site 1) gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hIL21R

Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210031
Validation Data：Presence

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.

Mice

Col2a1-2A-CreERT2

Strain Name：C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18029
Validation Data：Presence  |  Publications：1piece

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

hRSPO1

Strain Name：C57BL/6Smoc-Rspo1tm1(hRSPO1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225041
Validation Data：Presence

The endogenous mouse Rspo1 gene was replaced by human RSPO1 gene.

Mice

Foxp3-IRES-tdTomato-2A-Cre

Strain Name：C57BL/6Smoc-Foxp3em3(IRES-tdTomato-2A-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190119
Validation Data：Presence

A IRES-tdTomato-2A-Cre expression cassette was knocked into the Foxp3 gene stop codon site. This strain is useful in studying regulatory T cell in autoimmunity, especially in type 1 diabetes.

Mice

hLILRB4

Strain Name：C57BL/6Smoc-Lilrb4atm1(hLILRB4 )Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210024
Validation Data：Presence

The endogenous mice Lilrb4a gene was completely or partially replaced by human LILRB4 gene via CRISPR/Cas9 mediated recombination.

Mice

R26-hCD46-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-hCD46-IRES-tdTomato-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190087
Validation Data：Presence

These mice harbor a SA-human CD46-IRES-tdTomato-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hPD-L1/hVEGFR2

Strain Name：C57BL/6Smoc-Cd274tm1(hCD274)Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000102

hPD-L1(NM-HU-00062) was crossed with hKDR(NM-HU-00098) to generate hPD-L1/hKDR.

Mice

hIL10RA

Strain Name：C57BL/6Smoc-Il10ratm1(hIL10RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215072
Validation Data：Presence

The endogenous mouse Il10ra gene was replaced by human IL10RA gene.

Mice

hSERPINA1

Strain Name：C57BL/6Smoc-Serpina1etm1(hSERPINA1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225055
Validation Data：Presence

The endogenous mouse Serpina1e gene was replaced by human SERPINA1 gene.

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