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Nkx2-5-IRES-Cre

Strain Name：C57BL/6Smoc-Nkx2-5^{em1(IRES-Cre-WPRE-polyA)Smoc}
Strain State：Repository Live | Cat. NO.：NM-KI-200152

A IRES-Cre-WPRE-polyA expression cassette was knocked into the Nkx2-5 gene stop codon site.

Esr1-KO

Strain Name：C57BL/6Smoc-Esr1^em1Smoc Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190631

Esr1-KO mice (Stock No.NM-KO-190631）carry a knockout allele derived from the targeted deletion of exon 3. While Esr1-KO(2) mice (Stock No.NM-KO-200651) carrying the exon 4 deletion.Esr1-KO(3) mice (Stock No.210243) carrying the exon 4 deletion.

Regional delivery of mesothelin-targeted chimeric antigen receptor T-cell effectively and safely targets colorectal...

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FYB1-targeted modulation of CAPG promotes AML progression

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Webinar on Advances in Antibody-Drug Conjugates (ADCs) Development & Preclinical Models

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Join us for a webinar on June 26th, 2024, exploring the development and preclinical evaluation of Antibody-Drug Conjugates (ADCs). Learn from Dr. Hua Wei, VP of the Industrial Clients Department at GenoBioTX, about ADC components, mechanisms, historical evolution, and future directions.

New Service Launch: Mouse Bone Metastasis Cancer Model and Pain-Related Behavior Assessment!

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We are excited to announce that GenoBioTX has launched a new service featuring mouse bone metastasis cancer models and pain-related behavior assessment, designed to support cancer research and pain management effectively.

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

Join Our Webinar: Applications of Humanized Mouse Models in Preclinical Research

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Join GenoBioTX's webinar on July 25th to explore the latest advancements in humanized mouse models for preclinical research. Learn how these models are transforming targeted therapy development across various diseases. Featuring expert insights from Dr. Derek Reznik, discover the generation and application of humanized immune system models in oncology drug development. Don't miss this opportunity to enhance your knowledge in cutting-edge preclinical therapeutic advancements. Register now!

What are genetically engineered mice?

mouse genome point mutation transgene

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