Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6JSmo-Grb14em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201628
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Strain Name：C57BL/6JSmo-Greb1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-251093
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Strain Name：C57BL/6JSmo-Grem2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200845
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Strain Name：C57BL/6JSmo-Grhprem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-210151
Disease Connection：primary hyperoxaluria type 2
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Strain Name：C57BL/6JSmo-Gria1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190582
Research Application：Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes.This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors.
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Strain Name：C57BL/6JSmo-Gria3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190967
Research Application：Nervous system, LTP action, epilepsy
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