Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

mouse
Strain Name:C57BL/6JSmo-Tnfsf4tm1(hTNFSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00070
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Tnfsf4tm2(TNFSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200005
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Parp14tm1(hPARP14)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234703
mouse
Strain Name:C57BL/6JSmo-Pcsk9tm2(hPCSK9)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00075
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Pcsk9tm2(hPCSK9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230151
mouse
Strain Name:C57BL/6JSmo-Pcsk9tm2(hPCSK9)Angptl3tm1(hANGPTL3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-231369
mouse
Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00015
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Pdcd1tm2(hPDCD1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-235087
mouse
Strain Name:BALB/cJSmo-Pdcd1tm1(hPDCD1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190079
Research Application:Immunotherapy,cancer research,drug screening
mouse
Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1)Cd8atm1(V5-IRES-Akaluc-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210373
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