Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

mouse
Strain Name:C57BL/6JSmo-Nlrp3tm1(hNLRP3)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234380
mouse
Strain Name:C57BL/6JSmo-Notch1tm(hNOTCH1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230038
mouse
Strain Name:C57BL/6JSmo-Notch3tm(hNOTCH3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230037
mouse
Strain Name:C57BL/6JSmo-Npm1tm1(hNPM1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230146
mouse
Strain Name:C57BL/6JSmo-Npr3tm1(hNPR3)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234682
mouse
Strain Name:C57BL/6JSmo-Nr1h2tm1(hNR1H2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-234706
mouse
Strain Name:C57BL/6JSmo-Nr1i2tm3(hNR1I2)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000066
Research Application:Pharmacokinetic-related model
mouse
Strain Name:C57BL/6JSmo-Nr1i3tm2(hNR1I3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200253
mouse
Strain Name:C57BL/6JSmo-Nr3c1tm1(hNR3C1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225058
mouse
Strain Name:C57BL/6JSmo-Nrp1tm1(hNRP1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225046
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