U-GEMMs

代谢心血管疾病模型

代谢心血管疾病包括2型糖尿病、心脏代谢紊乱、高脂血症、动脉粥样硬化、高血压等,这类慢性病严重影响人的生活质量,并会带来沉重的经济负担。南模生物自主构建了多种代谢心血管疾病模型小鼠,可助力代谢心血管疾病的基础研究和药物开发。

Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190077
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190065
Disease Connection:breast cancer, CLOVES syndrome, ovarian cancer, brain glioma
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Krasem4(LSL-G12D)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-234153
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200017
Research Application:Non-alcoholic fatty liver disease
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem(SA-polyA-CAG-LSL-TPM3-NTRK1-IRES-luc-2A-tdTomato-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190098
Research Application:Colorectal carcinoma related.
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-FRT-LSL-Kras(G12C)-IRES-Luciferase-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200323
Mice
Strain Name:BALB/cAnSmoc-Gt(ROSA)26Sorem2(CAG-FRT-LSL-Kras(G12C)-IRES-Luciferase-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200324
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Trp53tm2(flox)Krasem4(LSL-G12D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-234519
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-Notch1C-IRES-nEGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200036
Research Application:Spontaneous tumor model
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200035
Research Application:Medulloblastoma
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