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Models

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Mice

Uox-KO(2)

Strain Name：C57BL/6Smoc-Uoxem1Smoc  
Strain State：Repository Live | Cat. NO.：NM-KO-191205

Uox-KO(2) mice(Stock No.NM-KO-191205）carry a knockout allele derived from the targeted deletion of exon 3-4.

Mice

Uox-Flox

Strain Name：C57BL/6Smoc-Uoxem1(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-230459

These mice carry loxP sites flanking exon 3-4 of Uox When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Uox gene.

Mice

Uox-Flox/Alb-Cre

Strain Name：C57BL/6Smoc-Uoxem1(flox)Tg(Alb-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-XA-242357

The Uox-Flox was crossed with Alb-Cre to generate Uox-Flox/Alb-Cre mice.

Mice

hXDH/Uox-KO

Strain Name：C57BL/6Smoc-Xdhtm2(hXDH)SmocUoxem1  
Strain State：Developing | Cat. NO.：NM-XA-252722

The hXDH(2) (NM-HU-240110) was crossed with Uox-KO(2)(NM-KO-191205) to generate hXDH(2)/Uox-KO(2) mice.

Literature

Knockout of the urate oxidase gene provides a stable mouse model of hyperuricemia associated with metabolic disorders

Model Organisms：小鼠 Product & Service：Uox Research field：kidney

尿酸氧化酶 uricase Uox 尿酸酶 高尿酸血症 hyperuricemia HUA

Published date：2017-07-01 | References：Kidney Int

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