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Ncan-Flox

Strain Name：C57BL/6Smoc-Ncan^{em1(flox)Smoc}
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Ncan gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ncan gene.

Lefty1-Flox

Strain Name：C57BL/6Smoc-Lefty1^{em1(flox)Smoc}
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Lefty1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lefty1 gene.

Tsc22D1-KO

Strain Name：C57BL/6Smoc-Tsc22D1^em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 1 of Tsc22D1 gene was deleted to generate Tsc22D1 knockout mice.

Txnl4b-KO

Strain Name：C57BL/6Smoc-Txnl4B^em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191153

Exon 2-4 of Txnl4b gene was deleted to generate Txnl4b knockout mice.

MC38-hTGFβ

Strain Name：MC38-Igs2^{em1(hTGFβ)/Smoc}
Strain State ： Validation of tumorigenic capacity completed |  Cat. NO.：NM-S13-TM63

A TGFβ expression cassette was knocked into the H11 locus.

MC38-hCD73/hTGFβ

Strain Name：MC38-Igs2^{em1(hCD73/hTGFβ)Smoc}
Strain State ： Validation of target gene expression completed |  Cat. NO.：NMC-230026

CD73/TGFβ gene humanized MC38 cell line

MC38-H11-hCD39/hTGFβ

Strain Name：MC38-Igs2^{em1(hCD39/hTGFβ)Smoc}
Strain State ： Validation of target gene expression completed |  Cat. NO.：NMC-230027

CD39/TGFβ gene humanized MC38 cell line

FAF1 phosphorylation by AKT accumulates TGF-beta type II receptor and drives breast cancer metastasis

Model Organisms：小鼠 Product & Service：Faf1 Research field：Breast cancer

TGF-β 肿瘤转移 抑癌因子 促癌因子 EIIa-Cre 广泛表达Cre

Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium

Model Organisms：小鼠 Product & Service： Npr3-CreER、Wt1-CreER、Sox9-CreER 和 Nfatc1-2A-CreER Research field：Heart

遗传谱系示踪 心内膜弹性纤维增生症 TGFβ

Fibroblast-specific activation of Rnd3 protects against cardiac remodeling in diabetic cardiomyopathy via suppression...

Model Organisms：小鼠 Product & Service：Col1a2-2A-Cre Research field：