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Models

About 44 results
Mice

hTGFBR2(2)

Strain Name：C57BL/6Smoc-Tgfbr2tm(hTGFBR2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-230041

The endogenous mouse Tgfbr2 gene was replaced by human TGFBR2 gene.

Mice

hTGFBR2

Strain Name：C57BL/6Smoc-Tgfbr2tm1(hTGFBR2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-252006

The endogenous mouse Tgfbr2 gene was replaced by human TGFBR2 gene.

Mice

hTGFBR1

Strain Name：C57BL/6Smoc-Tgfbr1tm1(hTGFBR1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-252714

The endogenous mouse Tgfbr1 gene was replaced by human TGFBR1 gene.

Mice

hTGFB2

Strain Name：C57BL/6Smoc-Tgfb2tm1(hTGFB2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-242458

The endogenous mouse Tgfb2 gene was replaced by human TGFB2 gene.

Mice

Ncan-KO

Strain Name：C57BL/6Smoc-Ncanem1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 3-9 of Ncan gene was deleted to generate Ncan knockout mice.

Mice

Ncan-Flox

Strain Name：C57BL/6Smoc-Ncanem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Ncan gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ncan gene.

Mice

Lefty1-Flox

Strain Name：C57BL/6Smoc-Lefty1em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Lefty1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lefty1 gene.

Mice

Tsc22D1-KO

Strain Name：C57BL/6Smoc-Tsc22D1em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 1 of Tsc22D1 gene was deleted to generate Tsc22D1 knockout mice.

Mice

Txnl4b-KO

Strain Name：C57BL/6Smoc-Txnl4Bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191153

Exon 2-4 of Txnl4b gene was deleted to generate Txnl4b knockout mice.

Literature

FAF1 phosphorylation by AKT accumulates TGF-beta type II receptor and drives breast cancer metastasis

Model Organisms：小鼠 Product & Service：Faf1 Research field：Breast cancer

TGF-β 肿瘤转移 抑癌因子 促癌因子 EIIa-Cre 广泛表达Cre

Published date：2017-04-01 | References：Nat Commun

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