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Models

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Mice

Mir21a-KO

Strain Name：B6;129S-Mir21atm1.2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-00159

This Mir21a gene knockout strain was generated by crossing Mir21a-flox (NM-CKO-00051) mice with EIIa-Cre transgenic mice. Exon1 of Mir21a gene was removed.

Mice

Serpinb1a-Flox

Strain Name：C57BL/6Smoc-Serpinb1aem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2100886

These mice carry loxP sites flanking exon 3-4 of serpinB1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of serpinB1a gene.

Mice

R26-CAG-Cas9

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00120

These mice were established by crossing R26-(CAG-LSL-Cas9) and EIIA mice together.

Mice

Serpinb1a-KO

Strain Name：C57BL/6Smoc-Serpinb1aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-202117

Exon 3-4 of Serpinb1a gene was deleted to generate Serpinb1a knockout mice.

Literature

FAF1 phosphorylation by AKT accumulates TGF-beta type II receptor and drives breast cancer metastasis

Model Organisms：小鼠 Product & Service：Faf1 Research field：Breast cancer

TGF-β 肿瘤转移 抑癌因子 促癌因子 EIIa-Cre 广泛表达Cre

Published date：2017-04-01 | References：Nat Commun

Literature

Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice

Model Organisms：小鼠 Product & Service：Lactoferrin Lf Research field：Immune system

乳铁蛋白 EIIa Cre

Published date：2014-01-01 | References：PLoS One

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