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Models

About 8 results
Mice

F8-KO

Strain Name：B6.129S-F8tm1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00012

F8-KO mice (Stock No.NM-KO-00012）carry a knockout allele derived from the targeted deletion of exon 16-19. While F8-KO(2) mice (Stock No.NM-KO-200608) carrying the exon 1-26 deletion.

Mice

F8-KO(2)

Strain Name：C57BL/6Smoc-F8em3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200608

F8-KO(2) mice (Stock No.NM-KO-200608）carry a knockout allele derived from the targeted deletion of exon 1-26. While F8-KO mice (Stock No.NM-KO-00012) carrying the exon 16-19 deletion.

Mice

Rag2/F8-KO

Strain Name：C57BL/6Smoc-Rag2em2F8tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-220025

Rag2-KO(NM-KO-190429) was crossed with F8-KO(NM-KO-00012) to generate Rag2/F8-KO mice.

Mice

Cd4/F8-KO

Strain Name：C57BL/6Smoc-Cd4em3F8tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-220026

Cd4-KO(2)(NM-KO-190441) was crossed with F8-KO(NM-KO-00012) to generate Cd4/F8-KO mice.

Mice

F8-Flox

Strain Name：C57BL/6Smoc-F8em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-231276

These strains carry loxP sites flanking exon 2-3 of F8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of F8 gene.

Mice

F7-Flox

Strain Name：C57BL/6Smoc-F7em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of F7 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of F7 gene.

Mice

F7-KO

Strain Name：C57BL/6Smoc-F7em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-225122

Exon 2 of F7 gene was deleted to generate F7 knockout mice.

Literature

Pharmacokinetics and pharmacodynamics of SCT800, a new recombinant FVIII, in hemophilia A mice

Model Organisms：小鼠 Product & Service：F8-KO Research field：Hemophilia

FVIII hemophilia A

Published date：2016-03-01 | References：Acta Pharmacol Sin

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