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Mice

hIL5/hIL5R(3)

Strain Name：C57BL/6Smoc-Il5em3(hIL5)Il5raem3(hIL5RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220011
Validation Data：Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

Itgax-tdTomato-Luc

Strain Name：C57BL/6Smoc-Itgaxem3(IRES-tdTomato-luci)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190116
Validation Data：Presence

A IRES-tdTomato-luci expression cassette was knocked into the Itgax gene stop codon site.

Mice

Plin1-2A-DreERT2

Strain Name：C57BL/6Smoc-Plin1em1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190034
Validation Data：Presence

A 2A-DreERT2 expression cassette was knocked into the Plin1 gene stop codon site.

Mice

H11-CAG-RSR-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18009
Validation Data：Absence

These mice harbor a CAG-Rox-STOP-Rox-tdTomato conditional expression cassette in mouse H11 locus via homologous recombination.

Mice

Dicer1-Flox

Strain Name：C57BL/6Smoc-Dicer1em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200158
Validation Data：Absence

These mice carry loxP sites flanking exon 23 of Dicer1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dicer1 gene.

Mice

Slc6a4-Cre

Strain Name：C57BL/6Smoc-Slc6a4em1(iCre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200115
Validation Data：Presence

A iCre-pA expression cassette was knocked into the Slc6a4 gene start codon site. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the neurological disorders such as addiction and depression.

Mice

hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)Sirpatm4(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220143
Validation Data：Absence

hSIRPA/hCD47(BALB/c)(NM-HU-210020) mice was crossed with hPD-1/ hPD-L1(BALB/c)(NM-HU-220142) mice to generate hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c) mice.

Mice

Pgr-IRES-Cre

Strain Name：C57BL/6Smoc-Pgrem1(IRES-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200150
Validation Data：Presence

A IRES-Cre expression cassette was knocked into the Pgr gene stop codon site.

Mice

Hcn4-DreERT2

Strain Name：C57BL/6Smoc-Hcn4em1(kozak-DreER-WPRE-A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200199
Validation Data：Absence

A kozak-DreER-WPRE-pA expression cassette was knocked into the Hcn4 gene start codon site.

Mice

R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190010
Validation Data：Absence

A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.

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