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Pharmacological inhibition of MYC to mitigate chemoresistance in preclinical models of squamous cell carcinoma

Model Organisms：小鼠 Product & Service：- Research field：

Knockout of the urate oxidase gene provides a stable mouse model of hyperuricemia associated with metabolic disorders

Model Organisms：小鼠 Product & Service：Uox Research field：kidney

尿酸氧化酶 uricase Uox 尿酸酶 高尿酸血症 hyperuricemia HUA

Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model

Model Organisms：小鼠 Product & Service：NRSF Research field：Nervous System

癫痫 CamKIIa-iCre

The deficiency of NRSF/REST enhances the pro-inflammatory function ofastrocytes in a model of Parkinson's disease

Model Organisms：Mouse Product & Service：NRSF Research field：Parkinson

Parkinson

PANoptosis Features, a Humanized NSG Murine Model of Sjogren's Syndrome

Model Organisms：小鼠 Product & Service：- Research field：

Identification of apoptosis and macrophage migration events in paraquat-induced oxidative stress using a zebrafish model

Model Organisms：斑马鱼 Product & Service：- Research field：Drug toxicity

凋亡 药物效应 百草枯 巨噬细胞 氧化应激

Parkin overexpression ameliorates hippocampal long-term potentiation and beta-amyloid load in an Alzheimer's disease...

Model Organisms：小鼠 Product & Service：NSE-globin-parkin Research field：Nervous System

阿尔兹海默症 AD APP/PS1

Pro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models.

Model Organisms：Mouse Product & Service：c-Rel-luc Research field：parkinson

parkinson

4-Phenylbutyrate restored γ-aminobutyric acid uptake and reduced seizures in SLC6A1 patient variant-bearing cell and...

Model Organisms：小鼠 Product & Service：Slc6a1-S295L(NM-KI-190014) Research field：Rare disease

Chemokine Receptors CCR6 and PD1 Blocking scFv E27 Enhances Anti-EGFR CAR-T Therapeutic Efficacy in a Preclinical...

Model Organisms：小鼠 Product & Service：M-NSG Research field：Non-Small Cell Lung Carcinoma