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Spred1-Flox

Strain Name：C57BL/6Smoc-Spred1^{em1(flox)Smoc}
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200299

This product was constructed with reference to the literature (PubMed ID: 21668589), in which loxP sites were inserted on both sides of exon 7 in the Spred1 gene transcript ENSMUST00000028829. The floxed region does not encompass the complete transcript ENSMUST00000110901.

Col1a1-tetO-EML4-ALK

Strain Name：C57BL/6Smoc-Col1a1^{tm1(TetO-EML4-ALK)Smoc}
Strain State：Sperm cryopreservation | Cat. NO.：DM-KI-251860

The human EML4-ALK gene was cloned into a TetO-EML4-ALK construct and microinjected into FVB zygotes, where it was inserted into the mouse Col1a1 locus. This strain was donated by the laboratory of Academician Liang Chen at Jinan University. Any published research papers or other forms of literature should cite: "Zhou Q, Yang T, Yu X, et al. Lanatoside C activates the E3 ligase STUB1 to inhibit FOXP3 transcriptional activity and promote antitumor immunity. EMBO Mol Med. 2025;17(3):563-588. doi:10.1038/s44321-025-00200-y"

Snx3-KO

Strain Name：C57BL/6Smoc-Snx3^em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201912

Snx3-KO mice (Stock No.NM-KO-201912) carry a knockout allele derived from the targeted deletion of exon 2-3. While Snx3-KO(2) mice(Stock No.NM-KO-210172）carrying the exon 3 deletion. It has been reported in the literature that homozygous for this gene knockout will die in the embryonic stage.

Snx3-KO(2)

Strain Name：C57BL/6Smoc-Snx3^emSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210172

Snx3-KO(2) mice(Stock No.NM-KO-210172） carry a knockout allele derived from the targeted deletion of exon 3. While Snx3-KO mice(Stock No.NM-KO-201912）carrying the exon 2-3 deletion. It has been reported in the literature that homozygous for this gene knockout will die in the embryonic stage.

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Study of Gene Functions

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