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Pharmacodynamics Analysis & Evaluation

Based on the U-GEMM repository, the pharmacodynamics evaluation service from Shanghai Model Organisms can conduct main pharmacodynamics study on the drugs for anti-inflammatory-immunity, antineoplastic, cardiovascular system, respiratory system and metabolic diseases,etc, satisfy the study requirements of different layers of in vivo experiments, mechanism investigation and molecular biological study, and confirm the effectiveness and safety of new drug(s).

Popular Model Organisms

genetically modified organisms transgenic organisms genetically modified organisms examples

Model organisms are instrumental to the study of gene functions. Gene editing technology has always played a crucial role in the research on gene functions, diseases and drug discovery, through its application in genetic engineering of model organisms, mimicking of human diseases, as well as observation of physiological or pathological changes. In particular, the CRISPR/Cas9 technology has achieved remarkable breakthroughs in recent years, significantly improving the efficiency of genetic engineering in model organisms, and facilitating more extensive and in-depth applications of animal models in various research fields.

Aging and Longevity Research

Humans have always been fascinated with the study of aging. Despite experiencing thousands of years of civilization, we have yet to clearly identify the mechanisms of aging. Either from the perspective of drug development or genetic research, the study of aging is undoubtedly a worthy cause.

Immunology and Inflammation

Inflammatory mouse

Shanghai Model Organisms provides a variety of mouse models of inflammation including exarteritis, chemotherapy-induced intestinal inflammation and inflammatory bowel disease. These models can be applied in researches on the mechanism of inflammation, evaluation of drug efficacy, and others.

Behavioral Analysis

study of animal behavior behavioral analysis

Shanghai Model Organisms' rodent behavioral analysis platform is equipped with a variety of experimental instruments used to study the classical behaviors of mice. Shanghai Model Organisms can provide single-item or complete sets of mouse behavioral analysis to assist you with your research in neurology, physiology, drug development, and drug efficacy evaluation. The Noldus behavioral analysis system is used to more comprehensively and accurately reflect the neurological and mental states of mice.

Research on Diseases

genetics diseases studies diseases research diseases

Shanghai Model Organisms provides a professional R&D platform for genetically-engineered mouse, zebrafish and nematode models, a service platform for phenotyping, and a rich repository of disease mouse models to support your studies on disease genetics, pathogenesis, drug treatments, and more.

Development of Formulation Process

U-GEMMsモデルリソースライブラリには

U-GEMMsモデルリソースライブラリには、KOモデルライブラリ、CKOモデルライブラリ、Find Cre ツールボックスマウス、遺伝的ヒト化マウス、免疫不全モデル、レポーターツールボックスマウス、蛍光トレーサーツールボックスマウス、遺伝性疾患モデルなどの複数のモデルを含む6000以上のモデルがあり、多くの人気分野をカバーしており、実験周期を効果的に短縮します。

U-GEMM Repository

The U-GEMM Repository has more than 6000 Genetically Engineered Mice & Rat Models, including KO , Flox，Cre/Dre, gene humanized knockin, Immunodeficiency, reporter Knockin , genetic disease and other models. You can Search for Mouse & Rat Models by Name, Catalog Number or Keyword.

U-GEMMs 모델 리소스 라이브러리

U-GEMMs 모델 리소스 라이브러리는6000가지가 넘는 모델을 보유하고 있으며, KO 모델 라이브러리，CKO 모델 라이브러리，Find Cre 도구 마우스，유전자 인간화 마우스，면역 결핍 모델，리포터 유전자 도구 마우스，형광 추적 도구 마우스，유전 질환 모델 등 여러 모델들이 있습니다. 여러 인기 영역에서 효과적으로 실험주기를 단축시킵니다!