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Metabolic Analysis

Metabolic analysis

There are many mice models used to mimic human metabolic diseases, such as diabetes and obesity, which are caused by nutritional imbalances and metabolic disorders. The detection and analysis of sugar and lipid metabolism phenotypes in these model mice are crucial for the establishment of model mice, the study of disease progression, and the research on the pathogenesis. Shanghai Model Organisms can help your research on metabolism by providing you with a series of testing tools for glucose and lipid metabolisms.

Popular Model Organisms

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Model organisms are instrumental to the study of gene functions. Gene editing technology has always played a crucial role in the research on gene functions, diseases and drug discovery, through its application in genetic engineering of model organisms, mimicking of human diseases, as well as observation of physiological or pathological changes. In particular, the CRISPR/Cas9 technology has achieved remarkable breakthroughs in recent years, significantly improving the efficiency of genetic engineering in model organisms, and facilitating more extensive and in-depth applications of animal models in various research fields.

SmocMab Fully-human Antibody Transgenic Mouse

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Services

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Shanghai Model Organisms offers a full range of model organism services, including model customization services, research-ready models, breeding, phenotyping and drug screening. Mouse, rat, zebrafish and C. elegans models are available to meet different research needs.

Why IL-2 Still Holds Promise in Therapeutics of Cancer and Autoimmunity

GEMM-Derived Allografts

Research on Diseases

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Shanghai Model Organisms provides a professional R&D platform for genetically-engineered mouse, zebrafish and nematode models, a service platform for phenotyping, and a rich repository of disease mouse models to support your studies on disease genetics, pathogenesis, drug treatments, and more.

P53 CKO Mouse Model

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Our own-developed mouse model of p53 conditional knockout (p53-CKO) can be mated with mice carrying tissue-specific Cre expression to obtain mice with homozygous deletion of p53 in specific tissues or cells. These mice can be used for tumorigenesis and tumor mechanistic studies.

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