Welcome to Advanced Search

hAppNL-F

Strain Name：C57BL/6Smoc-App^{tm3(hAppNL-F)/Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000087

The endogenous mouse App gene was replaced by human AppNL-F.

hTREM2

Strain Name：C57BL/6Smoc-Trem2^{em4(hTRem2)/Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000083

The endogenous mouse Trem2 gene was replaced by human TREM2 gene.

hAPOE4

Strain Name：C57BL/6Smoc-Apoe^{tm2(hAPOE4)Smoc}
Strain State：Repository Live | Cat. NO.：NM-HU-190002

This APOE4 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE4 corresponding sequence by homologous recombination.

hAPOE3

Strain Name：C57BL/6Smoc-Apoe^{tm3(hAPOE3)Smoc}
Strain State：Repository Live | Cat. NO.：NM-HU-190003

This APOE3 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE3 corresponding sequence by homologous recombination.

Sidt2-Flox

Strain Name：B6;129S-Sidt2^{tm1(flox)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00041

The Sidt2 flox allele has loxP sites flanking exon 2 of Sidt2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Snca-KO

Strain Name：C57BL/6Smoc-Snca^em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190380

This Snca knockout mouse model was generated by knocking out the exon4 region of the Snca.

Apoe-KO(SD)

Strain Name：SD-Apoe^em1Smoc Strain State：Repository Live | Cat. NO.：NR-KO-190003

Exon 2-4 of Apoe gene was deleted to generate Apoe knockout rat.

IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic...

Model Organisms：Mouse Product & Service：Rfx1 Research field：Epigenetic

E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases

Model Organisms：Mouse Product & Service：E4bp4 Research field：Autoimmune diseases

E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases

Model Organisms：小鼠 Product & Service：Rag2-KO Research field： Autoimmune diseases