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Why We Need Humanized Mice?

We Will be Attending AACR 2023 in Orlando!

Imaging Analysis

Animal imaging micro CT

shanghai Model Organisms provides services for microCT and IVIS whole-body in vivo imaging/fluorescence quantitative analysis of small animals.

Services

genetic engineering genetic animals genetic engineering examples

Shanghai Model Organisms offers a full range of model organism services, including model customization services, research-ready models, breeding, phenotyping and drug screening. Mouse, rat, zebrafish and C. elegans models are available to meet different research needs.

Smad4 CKO Mouse Model

Our own-developed Smad4 conditional knockout mice (Smad4-CKO) can be used to study cell proliferation and tumor suppression.

Brca1 CKO Mouse Model

Our own-developed Brca1 conditional knockout mice (Brca1-CKO) can be used to study breast cancer.

Rb1 CKO Mouse Model

With the ability to avoid the risk of death caused by homozygous and systemic knockout, our own-developed Rb1 conditional knockout mice (Rb1-CKO) can be used to study cancer, cell cycle or aging.

Liver Cancer PDX Model

PDX PDX models Patient-derived Xenografts

Patient-derived Xenografts (PDX) are advanced preclinical oncology models for drug development. It offers a far better alternative for preclinical drug evaluation as compared to the conventional cell line-derived xenograft model.

Construction of Overexpression Cell Line

Inflammation Models

inflammation diseases inflammation research inflammatory factors

Inflammation is a common yet important pathological process. Any factor that may cause tissue damage can lead to inflammation. Anomal inflammatory response may result in chronic inflammation, autoimmune diseases and even cancer. The regulation of inflammation-related genes is an important topic in the study of the development of inflammation.