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제브라피시·선충

제브라피시와 선충, 두 가지의 크고 작은 모델의 생물을 보유하고 있으며, 관련 기술 서비스를 제공합니다.

Popular Model Organisms

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Model organisms are instrumental to the study of gene functions. Gene editing technology has always played a crucial role in the research on gene functions, diseases and drug discovery, through its application in genetic engineering of model organisms, mimicking of human diseases, as well as observation of physiological or pathological changes. In particular, the CRISPR/Cas9 technology has achieved remarkable breakthroughs in recent years, significantly improving the efficiency of genetic engineering in model organisms, and facilitating more extensive and in-depth applications of animal models in various research fields.

Applications of Animal Models

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The model animal has played an important role in the history of life sciences and medicine, with a wide range of application in biology, medicine, molecular biology, molecular genetics, immunology and other fields.

Customize your genetically engineered models

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The scientific team at Shanghai Model Organisms Center, Inc, comprising of seasoned molecular biologists and technicians, is dedicated to providing highly customizable, genetically engineered models to global researchers.

Hemophilia Model

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The F8 and F9 gene knockout mice were generated by Shanghai Model Organisms Center (SMOC)

Cancer Model

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The laboratory mouse is widely considered as a valid and affordable model organism for studying human disease. Mouse models of cancer not only enable researchers to understand the genetic basis of tumor development in complicated and dynamic physiological systems, but also serve as irreplaceable tools for developing and testing new therapies.  Shanghai Model Organisms Center offers a variety of mouse models of cancer to meet the needs of both academic and industry partners.

Inflammation Models

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Inflammation is a common yet important pathological process. Any factor that may cause tissue damage can lead to inflammation. Anomal inflammatory response may result in chronic inflammation, autoimmune diseases and even cancer. The regulation of inflammation-related genes is an important topic in the study of the development of inflammation.

Liver Cancer PDX Model

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Patient-derived Xenografts (PDX) are advanced preclinical oncology models for drug development. It offers a far better alternative for preclinical drug evaluation as compared to the conventional cell line-derived xenograft model.

Mouse Models Expedite the Elucidation of AD Pathogenesis

Mouse

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Mice have long been the prime choice for model organisms. In more than 100 years, mice have been widely used by researchers in the fields of physiology, pathology, pharmacology, toxicology, and behavioral science. With the establishment of gene targeting technology, many researchers have made their way to the Nobel Prize.