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Literature

Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in...

Model Organisms: Product & Service:Il1b-Luc-Tg Research field:inflammatory diseases

Literature

Non-carcinogenic/non-nephrotoxic aristolochic acid IVa exhibited anti-inflammatory activities in mice

Model Organisms:小鼠 Product & Service:Tnf-IRES-Luc Research field:Anti-inflammatory

Literature

Programmed death protein 1 is essential for maintaining the anti-inflammatory function of infiltrating regulatory T...

Model Organisms:小鼠 Product & Service:Rag1-KO(Rag1-EGFP) Research field:Spinal cord injury

Literature

Tracing the dynamic expression of the Nfκb2 gene during inflammatory processes by in vivo bioluminescence imaging in...

Model Organisms:Mouse Product & Service:Nfkb2 pro-Luc Research field:chronic inflammatory diseases

Pages

New Service Launch: Mouse Bone Metastasis Cancer Model and Pain-Related Behavior Assessment!

Bone metastasis cancer model Pain-related behavior assessment Cancer-induced bone pain Bone cancer pain models Mouse bone metastasis model Animal models in cancer research Cancer research services Bone metastasis in mice Pain management in cancer

We are excited to announce that GenoBioTX has launched a new service featuring mouse bone metastasis cancer models and pain-related behavior assessment, designed to support cancer research and pain management effectively.

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Immunology and Inflammation

Inflammatory mouse

Shanghai Model Organisms provides a variety of mouse models of inflammation including exarteritis, chemotherapy-induced intestinal inflammation and inflammatory bowel disease. These models can be applied in researches on the mechanism of inflammation, evaluation of drug efficacy, and others.

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Inflammation Models

inflammation diseases inflammation research inflammatory factors

Inflammation is a common yet important pathological process. Any factor that may cause tissue damage can lead to inflammation. Anomal inflammatory response may result in chronic inflammation, autoimmune diseases and even cancer. The regulation of inflammation-related genes is an important topic in the study of the development of inflammation.

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Pharmacodynamics Analysis & Evaluation

Based on the U-GEMM repository, the pharmacodynamics evaluation service from Shanghai Model Organisms can conduct main pharmacodynamics study on the drugs for anti-inflammatory-immunity, antineoplastic, cardiovascular system, respiratory system and metabolic diseases,etc, satisfy the study requirements of different layers of in vivo experiments, mechanism investigation and molecular biological study, and confirm the effectiveness and safety of new drug(s).

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薬効の分析と評価

上海南方モデル動物バイオテクノロジー株式会社(Shanghai Model Organisms Center, Inc)の薬力学的評価サービスは、二十年の業界経験を積み重ねて、自社開発のU-GEMM®モデルマウスリソースライブラリーを利用して、抗炎免疫、抗腫瘍、心臓血管系、呼吸器系、代謝性疾患など薬物のスクリーニングをする為に、研究者様の求めに応じて 、in vivo 実験、メカニズムの検討、分子生物学研究などの異なるレベルの研究ニーズを満足し、新薬の有効性と安全性を明らかにし、国内外の製薬会社、生物医薬研究機関、新薬開発センター、大学の新薬開発機関などに、専門的な薬力学的評価サービスを提供しております。

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