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Cel-KO

Strain Name：C57BL/6Smoc-Cel^em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200825

Exon 2-3 of Cel gene was deleted to generate Cel knockout mice.

Cel-Flox

Strain Name：C57BL/6Smoc-Cel^{em1(flox)Smoc}
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Cel gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cel gene.

hBAFF (Balb/c)

Strain Name：C57BL/6Smoc-Igs2^{tm1(pAlb-hTNFSF13B-3'UTR var-polyA)Smoc}
Strain State：Repository Live | Cat. NO.：NM-KI-252776

pAlb-hTNFSF13B-3'UTR var-polyA expression cassette was knocked into the the Igs2 locus.

Parp9-Flox

Strain Name：C57BL/6Smoc-Parp9^{em1(flox)Smoc}
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234708

These strains carry loxP sites flanking exon 4 of Parp9 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Parp9 gene.

Dsg3-Flox

Strain Name：C57BL/6Smoc-Dsg3^{em1(flox)Smoc}
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234328

These strains carry loxP sites flanking exon 2-5 of Dsg3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dsg3 gene.

R26-CAG-LSL-Kras*G12C-IRES-Luc(BABL/c)

Strain Name：R26-CAG-LSL-Kras*G12C-IRES-Luc(BABL/c)
Strain State ： Validation of tumorigenic capacity completed |  Cat. NO.：NM-YD15

Derived from R26-CAG-LSL-Kras*G12C-IRES-Luc(BABL/c) mice(NM-KI-200324) spontaneous lung cancer model

What is the reason to use sentinel mice?

sentinel mice BALB/c mice C57BL/6 mice

New Service Launch: Mouse Bone Metastasis Cancer Model and Pain-Related Behavior Assessment!

Bone metastasis cancer model Pain-related behavior assessment Cancer-induced bone pain Bone cancer pain models Mouse bone metastasis model Animal models in cancer research Cancer research services Bone metastasis in mice Pain management in cancer

We are excited to announce that GenoBioTX has launched a new service featuring mouse bone metastasis cancer models and pain-related behavior assessment, designed to support cancer research and pain management effectively.

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

What is an inbred strain?

inbreeding coefficient inbreeding depression FVB