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Aging and Longevity Research

Humans have always been fascinated with the study of aging. Despite experiencing thousands of years of civilization, we have yet to clearly identify the mechanisms of aging. Either from the perspective of drug development or genetic research, the study of aging is undoubtedly a worthy cause.

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Mouse models for cancer research

Tumor bearing Mouse DEN model PDX model CDX model

Shanghai Model Organisms Center provides multiple types of tumor-bearing mouse models for cancer research and drug efficacy testing, including cell line-derived xenograft model (CDX) and patient-derived xenograft model (PDX). While PDX models better reflect the heterogeneity and diversity of human cancers, CDX models allow researchers to advance their pre-clinical drug development in a cost- and time-efficient manner.

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Excision and Regeneration of Tissue

liver regeneration subtotal gastrectomy

A mouse tissue regeneration model can be established by an operation of partial tissue excision. Such models can be used to study the changes in morphology, serology and metabolism during tissue regeneration, and hence lay the experimental foundation for studying the mechanisms regulating tissue regeneration.

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