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The deficiency of NRSF/REST enhances the pro-inflammatory function ofastrocytes in a model of Parkinson's disease

Model Organisms：Mouse Product & Service：NRSF Research field：Parkinson

Parkinson

PANoptosis Features, a Humanized NSG Murine Model of Sjogren's Syndrome

Model Organisms：小鼠 Product & Service：- Research field：

Identification of apoptosis and macrophage migration events in paraquat-induced oxidative stress using a zebrafish model

Model Organisms：斑马鱼 Product & Service：- Research field：Drug toxicity

凋亡 药物效应 百草枯 巨噬细胞 氧化应激

Parkin overexpression ameliorates hippocampal long-term potentiation and beta-amyloid load in an Alzheimer's disease...

Model Organisms：小鼠 Product & Service：NSE-globin-parkin Research field：Nervous System

阿尔兹海默症 AD APP/PS1

Chemokine Receptors CCR6 and PD1 Blocking scFv E27 Enhances Anti-EGFR CAR-T Therapeutic Efficacy in a Preclinical...

Model Organisms：小鼠 Product & Service：M-NSG Research field：Non-Small Cell Lung Carcinoma

Preclinical evaluation of the theranostic potential of 89Zr/177Lu-labeled anti-TROP-2 antibody in triple-negative...

Model Organisms：小鼠 Product & Service：- Research field：

Chemokine Receptor CCR2b Enhanced Anti-tumor Function of Chimeric Antigen Receptor T Cells Targeting Mesothelin in a...

Model Organisms： Product & Service：M-NSG Research field：Lung Carcinoma

Chimonanthus nitens var. salicifolius Aqueous Extract Protects against 5-Fluorouracil Induced Gastrointestinal...

Model Organisms：小鼠 Product & Service：- Research field：Digestive system

胃肠道黏膜炎 中药

Programmed death protein 1 is essential for maintaining the anti-inflammatory function of infiltrating regulatory T...

Model Organisms：小鼠 Product & Service：Rag1-KO(Rag1-EGFP) Research field：Spinal cord injury

Shanghai Model Organisms Jinshan R&D Base officially put into operation

Shanghai Model Organisms

After the base is put into operation, SMOC’s capability to provide genetically modified rat/mouse models and technical services including gene function research and drug development will be greatly enhanced.