In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6Smoc-Cdk6em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234171
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Strain Name：C57BL/6Smoc-Cdk7em(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220549
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Strain Name：C57BL/6Smoc-Cdk7em(flox)Foxp3em3(IRES-tdTomato-2A-iCre)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-234200
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Strain Name：C57BL/6Smoc-Cdk8em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-252773
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Strain Name：C57BL/6Smoc-Cdk9em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234609
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Strain Name：C57BL/6Smoc-Cdkal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234794
Disease Connection：type 2 diabetes mellitus
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Strain Name：C57BL/6Smoc-Cdkl1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-250759
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Strain Name：C57BL/6Smoc-Cdkl2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-250760
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