Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Cd3eem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2106077
Mice
Strain Name:C57BL/6Smoc-Cd3eapem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Cd3gem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Cd4em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2118244
Mice
Strain Name:C57BL/6Smoc-Cd40em(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-230190
Mice
Strain Name:C57BL/6Smoc-Cd40lgem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231310
Mice
Strain Name:C57BL/6Smoc-Cd44em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-231305
Mice
Strain Name:C57BL/6Smoc-Cd46em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231274
Mice
Strain Name:C57BL/6Smoc-Cd47tm1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-2114312
Mice
Strain Name:C57BL/6Smoc-Cd48tm1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231273
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