Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Cd300lfem1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-234058
Mice
Strain Name:C57BL/6Smoc-Cd300lgem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Cd302em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Cd320em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2113442
Mice
Strain Name:C57BL/6Smoc-Cd33em4(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-200002
Research Application:Therapeutic antibody target
Mice
Strain Name:C57BL/6Smoc-Cd34em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231270
Mice
Strain Name:C57BL/6Smoc-Cd36em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-200086
Research Application:Scavenger receptor and the innate immune system to the binding and uptake of ligand research
Mice
Strain Name:C57BL/6Smoc-Cd37em(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-230164
Mice
Strain Name:C57BL/6Smoc-Cd38em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2111797
Mice
Strain Name:C57BL/6Smoc-Cd3dem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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