SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6JSmo-Tnfrsf12atm(hTNFRSF12A)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-230046
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Strain Name：C57BL/6JSmo-Trem2tm4(hTREM2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000083
Research Application：Alzheimer's disease research;drug screening
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Strain Name：C57BL/6JSmo-Vsirtm1(hVSIR)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00118
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Vsig4tm1(hVSIG4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210004
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6JSmo-Ighmem1Ighdem1Sirpaem1(hSIRPA)Cd47em1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-232159
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Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-SIGLEC8-IRES-EGFP-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210137
Research Application：Fluorescent reporter Mice
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Strain Name：C57BL/6JSmo-Cd40tm1(hCD40)Rag2em1Il2rgem1Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000112
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Rag2em1Il2rgem1Sirpatm1(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000019
Research Application：Immunotherapy,drug screening
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