Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice
Strain Name:C57BL/6JSmo-Dmpkem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200635
Disease Connection:myotonic dystrophy type 1
Mice
Strain Name:C57BL/6Smoc-Dmrt1Iem1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Dmrt2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-231349
Mice
Strain Name:C57BL/6JSmo-Dmrta1em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2111514
Mice
Strain Name:C57BL/6JSmo-Dmrta2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2107239
Mice
Strain Name:C57BL/6Smoc-Dmrtb1em1Smoc
Strain State:Developing | Cat. NO.:NM-KO-260558
Mice
Strain Name:C57BL/6Smoc-Dmrtc1Aem1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Dmrtc1Bem1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Dmrtc1C1em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Dmrtc1C2em1Smoc
Strain State:Developing | Cat. NO.:TBD
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