Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice
Strain Name:C57BL/6Smoc-Dmac2Lem1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Dmbt1em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-202043
Mice
Strain Name:C57BL/6Smoc-Dmc1em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Dmdem3Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-200573
Disease Connection:Duchenne muscular dystrophy
Mice
Strain Name:C57BL/6JSmo-Dmdem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-234303
Mice
Strain Name:C57BL/6JSmo-Dmdem4Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-234304
Mice
Strain Name:C57BL/6JSmo-Dmdem5Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-234305
Mice
Strain Name:C57BL/6Smoc-Dmgdhem1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Dmknem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-205601
Research Application:secreted protein
Mice
Strain Name:C57BL/6JSmo-Dmp1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200634
Disease Connection:autosomal recessive hypophosphatemic rickets
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