Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6Smoc-Chrna2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200121
Research Application：Therapeutic antibody target
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Strain Name：C57BL/6Smoc-Chrna4em3Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-235012
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Strain Name：C57BL/6Smoc-Chrna5em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190568
Research Application：Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).
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Strain Name：C57BL/6Smoc-Chrna7emSmoc
Strain State：Repository Live | Cat. NO.：NM-KO-210112
Disease Connection：schizophrenia
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Strain Name：C57BL/6Smoc-Chrna7em1(Del1263751bp)Fan1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18062
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Strain Name：C57BL/6Smoc-Chrnb1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190936
Research Application：Nervous system, slow channel congenital muscle weakness syndrome
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Strain Name：C57BL/6Smoc-Chrnb2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2105377
Disease Connection：autism spectrum disorder
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