Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Ido1tm1(hIDO1)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00120
Research Application:cancer research,Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Lag3em1(hLAG3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190028
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00122
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1lg2em1(hPDCD1LG2)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190060
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200267
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Havcr2em1(hHAVCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200264
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1) Pvrigem1(hPVRIG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-231147
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Sema4dem1(hSemA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190033
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Siglec15em1(hSIGLEC15)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000093
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Sirpatm2(hSIRPA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000089
Research Application:Immunotherapy,drug screening
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