In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6Smoc-Ets1em(flox)/Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-220533
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Strain Name：C57BL/6Smoc-Ets1em(flox)Foxl1em(2A-CreERT2)1Smoc
Strain State：Developing | Cat. NO.：NM-CKO-233960
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Strain Name：C57BL/6Smoc-Ets2em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-233088
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Strain Name：C57BL/6Smoc-Etv1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-240746
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Strain Name：C57BL/6Smoc-Etv2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253747
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Strain Name：C57BL/6Smoc-Etv4em2(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-226136
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Strain Name：C57BL/6Smoc-Etv5em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-205130
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Strain Name：C57BL/6Smoc-Etv6em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200269
Disease Connection：breast cancer
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