Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Tnfrsf26em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Tnfrsf4em(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-230192
Mice
Strain Name:C57BL/6Smoc-Tnfrsf8em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231299
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9em(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-230186
Mice
Strain Name:C57BL/6Smoc-Tnfsf10em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2117533
Mice
Strain Name:C57BL/6Smoc-Tnfsf11em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2116383
Mice
Strain Name:C57BL/6Smoc-Tnfsf13bem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Tnfsf14em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231283
Mice
Strain Name:C57BL/6Smoc-Tnfsf15em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231323
Mice
Strain Name:C57BL/6Smoc-Tnfsf18em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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