CRISPR-Cas is a versatile genome editing technology for studying the functions of genetic elements. To broadly enable the application of CRISPR-associated nucleases(cas9, dcas9, Cas13d) in vivo, we established a set of Cre-dependent Cas knockin mouse models.
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Strain Name：C57BL/6Smoc-Tg(CAG-LSL-dCas9-SPH)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00025
Research Application：gene regulation tool,CRISPRa
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Strain Name：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00123
Research Application：gene regulation tool,CRISPRa
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18007
Research Application：CRISPRi,gene regulation tool
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00120
Research Application：gene editing, gene modification
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LNL-Cas9)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00038
Research Application：gene editing, gene modification
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LNL-Cas9-IRES-Luciferase-pA)
Strain State：Repository Live | Cat. NO.：NM-KI-18002
Research Application：Cas9,gene editing
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LNL-ddCas9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00063
Research Application：gene editing,gene modification
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Cas13d-IRES-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190063
Research Application：RNA editing,Cas13d
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Avi tag-dCas9-IRES-EGFP-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18031
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)
Strain State：Repository Live | Cat. NO.：NM-KI-18004
Research Application：gene regulation tool,CRISPRa
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