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Models

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Mice

Il18-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Il18em1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00032
Validation Data：Presence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il18.

Mice

Tnnt2-dCreERT2

Strain Name：C57BL/6JSmo-Tnnt2em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200015

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnnt2 gene start codon site.

Mice

hPD-1/hPD-L1(2)/hCCR8

Strain Name：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Cd274tm2(hPD-L1)Ccr8tm1(hCCR8)/Smoc
Strain State：Developing | Cat. NO.：NM-HU-210402

hPD-1(NM-HU-00015) and hPD-1(2)(NM-HU-190039) were crossed with hCCR8(NM-HU-190053) to generate hPD-1/hPD-L1(2)/hCCR8 mice.

Mice

Car4-DreERT2

Strain Name：C57BL/6JSmo-Car4em1(DreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200193

A DreERT2-Wpre-pA expression cassette was knocked into the Car4 gene start codon site.

Mice

hIL2/hIL2RA(BALB/c)

Strain Name：BALB/cJSmo-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220018
Validation Data：Presence

The endogenous mouse Il2 and Il2ra gene was replaced respectively by human IL2 and IL2RA gene.

Mice

hPD-L1/hCD27(2)

Strain Name：C57BL/6JSmo-Cd274tm1(hPD-L1)Cd27tm3(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200274

hPD-L1(NM-HU-00062) was crossed with hCD27(2)(NM-HU-190035)to generate hPD-L1/hCD27(2) mice.While hPD-L1/hCD27 (Stock No.NM-HU-18023) have been pulled from shelves for some reasons.

Mice

Slc17a6-CreERT2

Strain Name：C57BL/6JSmo-Slc17a6em2(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190011
Validation Data：Presence

This tamoxifen-inducible Slc17a6-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Slc17a6 gene.

Mice

Ncr1-2A-CreERT2

Strain Name：C57BL/6JSmo-Ncr1em4(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200004
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

C57BL/6

Strain Name：C57BL/6
Strain State：Repository Live | Cat. NO.：SM-001
Validation Data：Presence

It was the first mouse strain to have its genome sequenced. With black coat color, it is recognized as the "standard" inbred strain and provides genetic background for numerous mutant genes. It is characterized by stable strain properties, ease of breeding, uniform stress responses, and high precision in experimental results.

Mice

hIGHG4

Strain Name：C57BL/6JSmo-Ighg1tm1(hIGHG4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225092
Validation Data：Presence

The endogenous mouse Ighg1 gene was replaced by human IGHG4 gene.

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