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Models

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Mice

hDDR1

Strain Name:C57BL/6JSmo-Ddr1tm3(hDDR1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225086
Validation Data:Presence

The endogenous mouse Ddr1 gene was replaced by human DDR1 gene.

Mice

Erbb2-Flox

Strain Name:C57BL/6JSmo-Erbb2em(flox)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-220557

These mice carry loxP sites flanking exon 2 of Erbb2 When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Erbb2 gene.

Mice

hCTLA-4/hCCR8(BALB/c)

Strain Name:BALB/cJSmo-Ccr8tm1(hCCR8)Ctla4tm1(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220050

hCTLA4(BALB/c)(NM-HU-190078) was crossed with hCCR8(BALB/c)(NM-HU-2000048) to generate hCTLA4/hCCR8(BALB/c) mice.

Mice

hNECTIN4

Strain Name:C57BL/6JSmo-Nectin4tm1(hNECTIN4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210016
Validation Data:Presence

The endogenous mice Nectin4 gene was replaced by human NECTIN4 gene.

Mice

Avp-IRES-Cre

Strain Name:C57BL/6JSmo-Avpem1(IRES2-Cre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200142
Validation Data:Presence

A IRES2-Cre-WPRE-polyA expression cassette was knocked into the Avp gene stop codon site. Avp encodes arginine vasopressin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying hypertension.

Mice

hIFNGR1/hIFNGR2

Strain Name:C57BL/6JSmo-Ifngr1tm3(hIFNGR1)Ifngr2tm(hIFNGR2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220003
Validation Data:Presence

hIFNGR1(NM-HU-190076) was crossed with hIFNGR2(NM-HU-215010) to generate hIFNGR1/hIFNGR2 mice.

Mice

hPD-1(BALB/c)

Strain Name:BALB/cJSmo-Pdcd1tm1(hPDCD1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190079
Validation Data:Presence

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hFCRN(3)

Strain Name:C57BL/6JSmo-Fcgrttm3(hFCGRT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000032

The endogenous mouse Fcgrt gene was replaced by human FCGRT gene. While hFCRN(Stock No.NM-HU-00109)and hFCRN(2)(Stock No.NM-HU-190070) mice function similarly to hFCRN(3) mice,for more detailed information please contact our technical advisor.

Mice

hGNRHR

Strain Name:C57BL/6JSmo-Gnrhrtm(hGNRHR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220137
Validation Data:Presence

The endogenous mouse Gnrhr gene was replaced by human GNRHR gene.

Mice

hPD-L1/hSEMA4D

Strain Name:C57BL/6JSmo-Cd274tm1(hPD-L1)Sema4dtm1(hSemA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190034

hPD-L1(NM-HU-00062) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-L1/hSEMA4D.

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