Welcome to Advanced Search

Models

About 43,835 results
Mice

hTIGIT(BALB/c,2)

Strain Name：BALB/cJSmo-Tigittm4(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200245
Validation Data：Presence

The endogenous mice Tigit gene was replaced by human TIGIT gene.While hTIGIT(BALB/c) (Stock No.NM-HU-2000043) have been pulled from shelves for some reasons.

Mice

Cd79a-2A-Cre

Strain Name：C57BL/6JSmo-Cd79aem(2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220089
Validation Data：Presence

2A-Cre expression cassette was knocked into the Cd79a gene stop codon site.

Mice

Foxp3-IRES-tdTomato-2A-Cre

Strain Name：C57BL/6JSmo-Foxp3em3(IRES-tdTomato-2A-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190119
Validation Data：Presence

A IRES-tdTomato-2A-Cre expression cassette was knocked into the Foxp3 gene stop codon site. This strain is useful in studying regulatory T cell in autoimmunity, especially in type 1 diabetes.

Mice

R26-CAG-LSL-hHER2-IRES-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(SA-2xpolyA-CAG-LSL-HER2-luciferase-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190008

A SA-2xpolyA-CAG-LSL-HER2-IRES-Luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the HER2 protein.

Mice

hMELTF

Strain Name：C57BL/6JSmo-Meltftm(hMELTF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215011
Validation Data：Presence

The endogenous mouse Meltf gene was replaced by human MELTF gene.

Mice

hLAG3(BALB/c)

Strain Name：BALB/cJSmo-Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000051

The endogenous mouse Lag3 gene was replaced by human LAG3 gene.

Mice

hPSGL-1(2)

Strain Name：C57BL/6JSmo-Selplgtm2(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210026
Validation Data：Presence

The endogenous mice Selplg gene was completely or partially replaced by human SELPLG gene via CRISPR/Cas9 mediated recombination.

Mice

Il17b-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Il17bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00029

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17b.

Mice

hTNFR2/hIL2RA

Strain Name：C57BL/6JSmo-Tnfrsf1btm2(hTNFRSF1B)Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210408

hTNFRSF1B(NM-HU-190010) was crossed with hIL2RA(NM-HU-190064) to generate hTNFRSF1B/hIL2RA mice.

Mice

hIl5

Strain Name：C57BL/6JSmo-Il5tm3(hIL5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190001
Validation Data：Presence

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Email Back to top