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Models

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Mice

hF12

Strain Name：C57BL/6Smoc-F12em1(hF12)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210017
Validation Data：Presence

The endogenous mice F12 gene was replaced by human F12 gene.

Mice

Il6-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il6em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00011
Validation Data：Absence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il6.

Mice

R26-CAG-LSL-hFGFR3-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR3-IRES-Luciferase-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190083
Validation Data：Absence

These mice harbor a CAG-LSL-FGFR3-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.

Mice

hLAIR1/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Lair1em2(LAIR1)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220040
Validation Data：Absence

hLAIR1(NM-HU-2000011)，hPD-1(NM-HU-00015) and hPD-L1(NM-HU-00062) were crossed tegother to generate hLAIR1/hPD-1/hPD-L1 mouse.

Mice

Lyve1-IRES-Cre

Strain Name：C57BL/6Smoc-Lyve1em(IRES-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-220107
Validation Data：Presence

IRES-Cre expression cassette was knocked into the Lyve1 gene stop codon site.

Mice

hIL2/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Il2em3(hIL2)Il2rbem1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220145
Validation Data：Absence

hIL2RG(NM-HU-200007) and IL2RB(NM-HU-2000055) mice were crossed with hIL2(NM-HU-190048) mice to generate hIL2/hIL2RB/hIL2RG mice.

Mice

Pkd2l1-2A-CreERT2

Strain Name：C57BL/6Smoc-Pkd2l1em1(2A-CreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200310
Validation Data：Presence

2A-CreERT2-Wpre-pA expression cassette was knocked into the Pkd2l1 gene stop codon site.

Mice

hLILRB2-hLILRB3-Tg

Strain Name：C57BL/6Smoc-Tg(loxp-LILRB2-LILRB3-FRT-PGK-PuropolyA-FRT-lox2272)
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-220136
Validation Data：Presence

These transgenic mice harbor loxp-hLILRB2-hLILRB3-FRT-PGK-PuropolyA-FRT-lox2272 expression cassettes.

Mice

Kcng4-Cre

Strain Name：C57BL/6Smoc-Kcng4em1(iCre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200111
Validation Data：Presence

A iCre-pA expression cassette was knocked into the Kcng4 gene start codon site.

Mice

hCD3EDG/hPD-L1

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd274em1(hPD-L1) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220112
Validation Data：Absence

hCD3EDG(NM-HU-220120) mice were crossed with hPD-L1(NM-HU-00062) mice to generate hCD3EDG/hPD-L1 mice

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