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Models

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Mice

Sox2-2A-DreERT2

Strain Name：C57BL/6Smoc-Sox2em1(2A-DreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200059
Validation Data：Absence

A 2A-DreERT2 expression cassette was knocked into the Sox2 gene stop codon site.

Mice

Opn4-Cre

Strain Name：C57BL/6Smoc-Opn4em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200304
Validation Data：Presence

Cre-WPRE-polyA expression cassette was knocked into the Opn4 gene start codon site. The melanopsin gene (Opn4) encodes a functional photopigment. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying circadian rhythm regulation.

Mice

hIL3

Strain Name：C57BL/6Smoc-Il3em1(hIL3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190009
Validation Data：Absence

The endogenous mouse Il3 gene was replaced by human IL3 gene.

Mice

Dbt-KO

Strain Name：C57BL/6Smoc-Dbtem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200633
Validation Data：Absence

Exon 2 of Dbt gene was deleted to generate Dbt knockout mice.

Mice

Lgals3-KO

Strain Name：C57BL/6Smoc-Lgals3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190107
Validation Data：Absence

This Lgals3 knockout mouse model was generated by knocking out the exon 3-4 region of the Lgals3 .

Mice

R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190067
Validation Data：Absence

These mice harbor a CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Msln-DreERT2

Strain Name：C57BL/6Smoc-Mslnem1(kozak-DreER-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200200
Validation Data：Absence

A kozak-DreER-WPRE-pA expression cassette was knocked into the Msln gene start codon site.

Mice

Cldn16-KO

Strain Name：C57BL/6Smoc-Cldn16em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200632
Validation Data：Absence

Exon 2 of Cldn16 gene was deleted to generate Cldn16 knockout mice.

Mice

hSNCA

Strain Name：C57BL/6Smoc-Sncaem(hSNCA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220261
Validation Data：Presence

The endogenous mouse Snca gene was replaced by human SNCA gene.

Mice

Cdkal1-Flox

Strain Name：C57BL/6Smoc-Cdkal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234794
Validation Data：Absence

These strains carry loxP sites flanking exon 5 of Cdkal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cdkal1 gene.

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