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Models

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Mice

Pdgfra-Dre

Strain Name:C57BL/6Smoc-Pdgfraem(Dre-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-220193
Validation Data:Presence

Dre-WPRE-pA expression cassette was knocked into the Pdgfra gene start codon site.

Mice

Cd4-IRES-DTRGFP

Strain Name
Strain State: | Cat. NO.:
Validation Data:Absence

A IRES-DTREGFP expression cassette was knocked into the Cd4 gene stop codon site.

Mice

R26-CAG-LSL-hIDH1*R132H-IRES-Luc-2A-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH1(R132H)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190074
Validation Data:Absence

These mice harbor a CAG-LSL-IDH1(R132H)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Trpv1-IRES-Cre

Strain Name
Strain State: | Cat. NO.:
Validation Data:Absence

A Myc-IRES-Cre expression cassette was knocked into the Trpv1 gene stop codon site. Trpv1 is known as transient receptor potential cation channel, subfamily V, member 1. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying the pain caused by heat and capsaicin.

Mice

Dmp1-KO

Strain Name:C57BL/6Smoc-Dmp1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200634
Validation Data:Absence

Exon 4-6 of Dmp1 gene was deleted to generate Dmp1 knockout mice.

Mice

Ccl4-c-Rox-TGATAA-Stop-c-Rox-2A-Cre

Strain Name:C57BL/6Smoc-Ccl4em(c-Rox-TGATAA-Stop-c-Rox-2A-Cre-Wpre-pA)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225056
Validation Data:Absence

c-Rox-TGATAA-Stop-c-Rox-2A-Cre-Wpre-pA expression cassette was knocked into the Ccl4 gene .

Mice

Sirt3-KO

Strain Name:C57BL/6Smoc-Sirt3em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190368
Validation Data:Absence

This Sirt3 knockout mouse model was generated by knocking out the exon 2-3 region of the Sirt3.

Mice

Tfam-Flox

Strain Name:C57BL/6Smoc-Tfamtm1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-200173
Validation Data:Absence

These mice carry loxP sites flanking exon 10-13 of Tfam gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tfam gene.

Mice

R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-FGFR2-luciferase-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190007
Validation Data:Absence

A SA-2xpolyA-CAG-LSL-FGFR2-IRES-luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the FGFR2 protein.

Mice

Il1f9-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Il1f9em1(Luc-eGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00018
Validation Data:Absence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1f9.

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