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Models

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Mice

Pnliprp1-KO

Strain Name：B6;129S-Pnliprp1tm1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00005
Validation Data：Absence

Exon 1 to exon 8 were replaced with Neo cassette.

Mice

Sox10-KO

Strain Name：C57BL/6Smoc-Sox10em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200645
Validation Data：Absence

Exon 4-5 of Sox10 gene was deleted to generate Sox10 knockout mice.

Mice

R26-loxP-tdTomato-loxP-DTA

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm(SA-loxP-tdTomato-PGK-Neo-3xpA-loxP-DTA-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225003
Validation Data：Absence

SA-loxP-tdTomato-PGK-Neo-3xpA-loxP-DTA-pA expression cassette was knocked into the the Rosa26 locus.

Mice

Gpr132-KO

Strain Name：C57BL/6Smoc-Gpr132em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200979
Validation Data：Absence

Exon 3 of Gpr132 gene was deleted to generate Gpr132 knockout mice.

Mice

Lmna-c.C1827T

Strain Name：C57BL/6Smoc-Lmnatm1(G609G)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200284
Validation Data：Presence

These mice carry a G609G mutation of Lmna gene.

Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210358
Validation Data：Absence

hSIRPA(2)(NM-HU-18015)，hCD47（NM-HU-00050), hPD-1（NM-HU-00015）, hPD-L1（NM-HU-00062）was crossed together to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1 mice.

Mice

hLY96

Strain Name：C57BL/6Smoc-Ly96em1(hLY96)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210003
Validation Data：Presence

The endogenous mice Ly96 gene was replaced by human LY96 gene

Mice

Lepr-RSR-CreERT2

Strain Name：C57BL/6Smoc-Leprtm1(rox-stop-rox-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210112
Validation Data：Absence

rox-stop-rox-CreERT2-WPRE-polyA expression cassette was knocked into the Lepr gene.

Mice

hNKG2A/hCD94

Strain Name：C57BL/6Smoc-Nkg2tm1(hNKG2A)Cd94tm1(hCD94)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000016
Validation Data：Absence

The endogenous mouse Nkg2 and Cd94 gene was replaced by human NKG2A and CD94 gene.

Mice

hPD-1/hPD-L1/hTIGIT

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200267
Validation Data：Absence

hTIGIT（NM-HU-00053）,hPD-1（NM-HU-00015）,hPD-L1（NM-HU-00062）were crossed together to generate hPD-1/hPD-L1/hTIGIT mice

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