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Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220029
Validation Data：Absence

hSIRPA(2)(NM-HU-18015), hCD47(NM-HU-00050) and hPD-1(NM-HU-00015) was crossed with hPD-L1(2)(NM-HU-190039）to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1(2) mice.

Mice

Tigre-TetO-hVEGFA165-IRES-EGFP

Strain Name：C57BL/6Smoc-Igs7em(tetO-VEGFA165-IRES-EGFP-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-205000
Validation Data：Absence

tetO-VEGFA165-IRES-EGFP-polyA expression cassette was knocked into the TIGRE gene .

Mice

Prox1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Prox1em1(IRES-CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200119
Validation Data：Presence

A IRES-CreERT2-pA expression cassette was knocked into the Prox1 gene stop codon site. Prox1 encodes a transcription factor (prospero-related homeobox 1) that is necessary for the formation and maintenance of lymphatic vessels. When Prox1-IRES-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible Cre-mediated recombination will result in deletion of the floxed sequences in PROX1positive cells.

Mice

hCD3EDG/hTPBG

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Cd3dem1(hCD3D)Cd3gem1(hCD3G)Tpbgem1(hTPBG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220111
Validation Data：Absence

hCD3EDG(NM-HU-220120) mice were crossed with hTPBG(NM-HU-200239) mice to generate hCD3EDG/hTPBG mice

Mice

hIL2RB/hPD-1

Strain Name：C57BL/6Smoc-Il2rbem1(hIL2RB)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220036
Validation Data：Absence

hIL2RB(NM-HU-2000055) mice were crossed with hPD-1(NM-HU-00015) to generate hIL2RB/hPD-1 mice.

Mice

Park7-KO

Strain Name：C57BL/6Smoc-Park7em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191006
Validation Data：Absence

Exon 3-5 of Park7 gene was deleted to generate Park7 knockout mice.

Mice

Rag1-2A-Cre

Strain Name：C57BL/6Smoc-Rag1em(2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220088
Validation Data：Absence

2A-Cre expression cassette was knocked into the Rag1 gene stop codon site.

Mice

hPD-1/hTIGIT/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Tigitem1(hTIGIT) Havcr2em1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190029
Validation Data：Absence

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hTIM3(NM-HU-00054) to generate hPD-1/hTIGIT/hTIM3.

Mice

Il1f6-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1f6em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00017
Validation Data：Absence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1f6.

Mice

R26-CAG-LSL-hIDH2*R172K-IRES-Luci-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190076
Validation Data：Absence

These mice harbor a CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

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