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Models

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Mice

H11-CAG-RSR-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18009
Validation Data：Absence

These mice harbor a CAG-Rox-STOP-Rox-tdTomato conditional expression cassette in mouse H11 locus via homologous recombination.

Mice

hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)Sirpatm4(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220143
Validation Data：Absence

hSIRPA/hCD47(BALB/c)(NM-HU-210020) mice was crossed with hPD-1/ hPD-L1(BALB/c)(NM-HU-220142) mice to generate hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c) mice.

Mice

Pgr-IRES-Cre

Strain Name：C57BL/6Smoc-Pgrem1(IRES-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200150
Validation Data：Presence

A IRES-Cre expression cassette was knocked into the Pgr gene stop codon site.

Mice

Hcn4-DreERT2

Strain Name：C57BL/6Smoc-Hcn4em1(kozak-DreER-WPRE-A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200199
Validation Data：Absence

A kozak-DreER-WPRE-pA expression cassette was knocked into the Hcn4 gene start codon site.

Mice

R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190010
Validation Data：Absence

A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.

Mice

Myh11-2A-DreERT2

Strain Name：C57BL/6Smoc-Myh11em1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190037
Validation Data：Absence

A 2A-DreERT2 expression cassette was knocked into the Myh11 gene stop codon site.

Mice

Il7-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il7em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00092
Validation Data：Absence

A Luciferase-2a-egfp-polyA cassette was inserted at ATG site of mouse Il7 gene.

Mice

R26-Renilla-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-Renilla-Luc)-NSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00091
Validation Data：Absence

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Renilla-Luc gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.

Mice

Postn-2A-CreERT2

Strain Name：C57BL/6Smoc-Postnem(2A-CreERT2)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225034
Validation Data：Absence

2A-CreERT2 expression cassette was knocked into the Postn gene .

Mice

hIL17RA(BALB/c)

Strain Name：BALB/cAnSmoc-Il17raem1(hIL17RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220015
Validation Data：Presence

The endogenous mouse Il17ra gene was replaced by human IL17RA gene.

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