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Models

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Mice

hC1R

Strain Name：C57BL/6Smoc-C1raem1(hC1R)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000075
Validation Data：Presence

The endogenous mouse C1ra gene was replaced by human C1R gene.

Mice

Shh-EGFP-Cre

Strain Name：C57BL/6Smoc-Shhem1(EGFP-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200232
Validation Data：Absence

A EGFP-iCre expression cassette was knocked into the Shh gene start codon site.

Mice

hC1QA

Strain Name：C57BL/6Smoc-C1qaem1(hC1QA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-200282
Validation Data：Absence

The endogenous mice C1qa gene was replaced by human C1QA gene.

Mice

hCD28

Strain Name：C57BL/6Smoc-Cd28em2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190011
Validation Data：Presence

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Mice

hB7H3/hCD28

Strain Name：C57BL/6Smoc-Cd276em2(hCD276)Cd28em2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210353
Validation Data：Presence

hB7-H3(NM-HU-00107) was crossed with hCD28(NM-HU-190011) to generate hB7H3/hCD28 mice.

Mice

Cav1-KO

Strain Name：C57BL/6Smoc-Cav1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190930
Validation Data：Absence

Exon 3 of Cav1 gene was deleted to generate Cav1 knockout mice.

Mice

hAGT

Strain Name：C57BL/6Smoc-Agtem1(hAGT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225082
Validation Data：Presence

The endogenous mouse Agt gene was replaced by human AGT gene.

Mice

Wnt5b-IRES-CreERT2-2A-tdTomato

Strain Name：C57BL/6Smoc-Wnt5bem(IRES-CreERT2-P2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215083
Validation Data：Absence

IRES-CreERT2-P2A-tdTomato expression cassette was knocked into the Wnt5b gene .

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039
Validation Data：Presence

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

R26-CAG-LSL-hACE2-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200188
Validation Data：Presence

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.

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