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Models

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Mice

Nkx2-5-IRES-Cre

Strain Name：C57BL/6Smoc-Nkx2-5em1(IRES-Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200152
Validation Data：Presence

A IRES-Cre-WPRE-polyA expression cassette was knocked into the Nkx2-5 gene stop codon site.

Mice

Ywhaz-KO

Strain Name：C57BL/6Smoc-Ywhazem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-202154
Validation Data：Absence

Exon 4 of Ywhaz gene was deleted to generate Ywhaz knockout mice.

Mice

R26-SA-LSL-DTR-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-DTR-IRES-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210136
Validation Data：Absence

A SA-LSL-DTR-IRES-tdTomato expression cassette was knocked into via the Rosa26 locus.

Mice

Il4-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il4em1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00021
Validation Data：Presence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il4.

Mice

Bckdk-KO

Strain Name：C57BL/6Smoc-Bckdkem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-2101591
Validation Data：Absence

exon 9-12 of Bckdk gene was deleted to generate Bckdk knockout mice.

Mice

hPD-1/hPD-L1/hLAG3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Lag3em1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190028
Validation Data：Absence

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hPD-L1/hLAG3.

Mice

hTIGIT/hCCR8

Strain Name：C57BL/6Smoc-Tigitem1(hTIGIT)Ccr8em1(hCCR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210426
Validation Data：Absence

hTIGIT(NM-HU-00053) was crossed with hCCR8(NM-HU-190053) to generate hTIGIT/hCCR8 mice.

Mice

hIL3/hCSF2

Strain Name：C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190065
Validation Data：Presence

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.

Mice

hCD3EDG/hCD40

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Cd3dem1(hCD3D)Cd3gem1(hCD3G)Cd40em1(hCD40)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220116
Validation Data：Absence

hCD3EDG(NM-HU-220120) mice were crossed with hCD40(NM-HU-00076) to generate hCD3EDG//hCD40 mice.

Mice

hPD-1/hPD-L1(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220142
Validation Data：Absence

hPD-1(BALB/c)(NM-HU-190079) mice were crossed with hPD-L1(BALB/c ) (NM-HU-220028) mice to generate hPD-1/ hPD-L1(BALB/c) mice.

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