Welcome to Advanced Search

Models

About 43,970 results
Mice

Wdfy1-CreERT2

Strain Name：C57BL/6Smoc-Wdfy1em(Kozak-CreERT2-WPRE-pA )Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220121
Validation Data：Absence

Kozak-CreERT2-WPRE-pA expression cassette was knocked into the Wdfy1 gene start codon site.

Mice

hIL17RA

Strain Name：C57BL/6Smoc-Il17raem1(hIL17RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190049
Validation Data：Presence

The endogenous mouse Il17ra gene was replaced by human IL17RA gene.

Mice

Chga-CreERT2

Strain Name：C57BL/6Smoc-Chgaem(CreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204993
Validation Data：Presence

CreERT2-Wpre-pA expression cassette was knocked into the Chga gene.

Mice

Prom1-CreERT2

Strain Name：C57BL/6Smoc-Prom1em1(CreERT2-PolyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200169
Validation Data：Presence

A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells.

Mice

Sidt2-Flox

Strain Name：B6;129S-Sidt2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00041
Validation Data：Absence

The Sidt2 flox allele has loxP sites flanking exon 2 of Sidt2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Cd8a-IRES-DTRGFP

Strain Name：
Strain State： | Cat. NO.：
Validation Data：Absence

A IRES-DTREGFP expression cassette was knocked into the Cd8a gene stop codon site.

Mice

hKLRK1

Strain Name：C57BL/6Smoc-Klrk1em1(hKLRK1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190005
Validation Data：Presence

The endogenous mouse Klrk1 gene was replaced by human KLRK1 gene.

Mice

Ins2-DreERT2

Strain Name：C57BL/6Smoc-Ins2em2(DreERT2-Wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190039
Validation Data：Absence

A DreERT2-Wpre-polyA expression cassette was knocked into initiation codon ATG site of the Ins2 gene.

Mice

hLAG3/hCTLA-4

Strain Name：B6.129S-Lag3em1(hLAG3)Ctla4em1(hCTLA4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190018
Validation Data：Absence

This LAG3 and CTLA4 double knockin strain is established by crossing LAG3-HU and CTLA4-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hIL21/hIL21R

Strain Name：C57BL/6Smoc-Il21tm1(hIL21)Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220038
Validation Data：Presence

hIL21(NM-HU-200255) were crossed with hIL21R(NM-HU-210031) to generate hIL21/hIL21R mice.

Email Back to top