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Models

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Mice

Tyro3-KO

Strain Name:C57BL/6Smoc-Tyro3em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200558
Validation Data:Absence

Exon 3 of Tyro3 gene was deleted to generate Tyro3 knockout mice.

Mice

Krt14-2A-DreERT2

Strain Name:C57BL/6Smoc-Krt14em3(2A-DreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190125
Validation Data:Presence

A 2A-DreERT2 expression cassette was knocked into the Krt14 gene stop codon site.

Mice

hPD-1/hVISTA

Strain Name:C57BL/6Smoc-Visrem1(hVSIR)Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000092
Validation Data:Absence

hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hVISTA.

Mice

Acadvl-KO

Strain Name:C57BL/6Smoc-Acadvlem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200908
Validation Data:Absence

Exon 3-7 of Acadvl gene was deleted to generate Acadvl knockout mice.

Mice

hTNFa-Tg

Strain Name:C57BL/6Smoc-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-200004
Validation Data:Presence

These transgenic mice harbor hTNFa promoter-hTNFa-pA expression cassette.

Mice

hIL9(BALB/c)

Strain Name:BALB/cAnSmoc-Il9em3(hIL9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220012
Validation Data:Presence

The endogenous mouse Il9 gene was replaced by human IL9 gene.

Mice

Abcb8-Flox

Strain Name:C57BL/6Smoc-Abcb8em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-253536
Validation Data:Absence

These mice carry loxP sites flanking exon 3-6 of Abcb8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Abcb8 gene.

Mice

hLILRB4

Strain Name:C57BL/6Smoc-Lilrb4aem1(hLILRB4 )Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210024
Validation Data:Presence

The endogenous mice Lilrb4a gene was completely or partially replaced by human LILRB4 gene via CRISPR/Cas9 mediated recombination.

Mice

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18007
Validation Data:Presence

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

Mice

hIL13(BALB/c)

Strain Name:BALB/cAnSmoc-Il13em2(hIL13)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220019
Validation Data:Presence

The endogenous mouse Il13 gene was replaced by human IL13 gene.

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