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Mice

Tagln-2A-DreERT2

Strain Name：C57BL/6Smoc-Taglnem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215038
Validation Data：Presence

2A-DreERT2 expression cassette was knocked into the Tagln gene. Tagln-2A-DreERT2(2) (Stock No.NM-KI-215094) is similar to this strain.

Mice

Alms1-del(c.3802-3812)

Strain Name：C57BL/6Smoc-Alms1em(delc.3802-3812)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220067
Validation Data：Absence

These mice carry a del(c.3802-3812) mutation of Alms1 gene.

Mice

Sox10-2A-Cre

Strain Name：C57BL/6Smoc-Sox10em(2A-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-220066
Validation Data：Presence

2A-Cre expression cassette was knocked into the Sox10 gene stop codon site. The target gene is associated with pigment, and heterozygotes are recommended for mating in breeding.

Mice

Pax7-IRES-Cre

Strain Name：C57BL/6Smoc-Pax7em1(IRES-iCre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200120
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7.

Mice

hIL2RG/hIL2RB

Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Il2rbem1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210354
Validation Data：Presence

hIL2RG(NM-HU-200007) was crossed with hIL2RB(NM-HU-2000055) to generate hIL2RG/hIL2RB mice.

Mice

hCTLA-4(BALB/c)

Strain Name：BALB/cAnSmoc-Ctla4em1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190078
Validation Data：Presence

Obtained by backcrossing of NM-HU-00014，hCTLA-4 mice.

Mice

Cx3cr1-CreERT2

Strain Name：C57BL/6Smoc-Cx3cr1em1(creERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200157
Validation Data：Presence

A creERT2-WPRE-polyA expression cassette was knocked into the Cx3cr1 gene start codon site.

Mice

C1qa-KO

Strain Name：C57BL/6Smoc-C1qaemSmoc
Strain State：Repository Live | Cat. NO.：NM-KO-210110
Validation Data：Absence

exon 3 of C1qa gene was deleted to generate C1qa knockout mice.

Mice

hCTLA-4/4-1BB

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18020
Validation Data：Absence

This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hCD3EDG/hCD19

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Cd3dem1(hCD3D)Cd3gem1(hCD3G)Cd19em1(hCD19)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220109
Validation Data：Presence

hCD3EDG(NM-HU-220120) mice were crossed with hCD19(NM-HU-00110) mice to generate hCD3EDG/hCD19 mice.

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