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Models

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Mice

hIL2/hIL2RA(BALB/c)

Strain Name：BALB/cAnSmoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220018
Validation Data：Presence

The endogenous mouse Il2 and Il2ra gene was replaced respectively by human IL2 and IL2RA gene.

Mice

Mertk-KO

Strain Name：C57BL/6Smoc-Mertkem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200362
Validation Data：Absence

Exon 2 of Mertk gene was deleted to generate Mertk knockout mice.

Mice

hPD-1/hIL1B

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Il1bem3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210018
Validation Data：Absence

hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1

Strain Name：C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220068
Validation Data：Absence

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1(NM-HU-00015) mouse.

Mice

Cspg4-CreERT2-2A

Strain Name：C57BL/6Smoc-Cspg4em(CreERT2-P2A)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225033
Validation Data：Presence

CreERT2-P2A expression cassette was knocked into the Cspg4 gene .

Mice

hICOS

Strain Name：C57BL/6Smoc-Icosem1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00052
Validation Data：Presence

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(2)(Stock No.NM-HU-190030) mice function similarly to hICOS mice,for more detailed information please contact our technical advisor.

Mice

Agr2-2A-CreERT2(2)

Strain Name：C57BL/6Smoc-Agr2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-231956
Validation Data：Absence

The 2A-CreERT2-WPRE-pA expression cassette was knocked into the Agr2 gene stop codon site.

Mice

R26-CAG-LSL-hEGFR*L858R/T790M-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190068
Validation Data：Absence

These mice harbor a CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Lgr5-2A-DreERT2

Strain Name：C57BL/6Smoc-Lgr5em1(2A-DreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200178
Validation Data：Presence

A 2A-DreERT2 expression cassette was knocked into the Lgr5 gene stop codon site.

Mice

S100a4-2A-CreERT2

Strain Name：C57BL/6Smoc-S100a4em1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200024
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the S100a4 gene stop codon site.

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